Background: This gene encodes a member of the mucin family of proteins, which are highly glycosylated macromolecular components of mucus secretions. This family member is the major gel-forming mucin in mucus. It is a major contributor to the lubricating and viscoelastic properties of whole saliva, normal lung mucus and cervical mucus. This gene has been found to be up-regulated in some human diseases, including sinus mucosa of chronic rhinosinusitis (CRS), CRS with nasal polyposis, chronic obstructive pulmonary disease (COPD) and H. pylori-associated gastric disease, and it may be involved in the pathogenesis of these diseases.
Applications: ELISA, IHC
Name of antibody: MUC5B
Immunogen: Synthetic peptide of human MUC5B
Full name: mucin 5B, oligomeric mucus/gel-forming
Synonyms： MG1, MUC5, MUC9, MUC-5B
SwissProt: Q9HC84
ELISA Recommended dilution: 2000-5000
IHC positive control: Human breast cancer
IHC Recommend dilution: 25-100